Title: Motion Compensation for High Resolution CT Scans of Living Mice

Abstract: Imaging bones of living mice in an X-ray microscopy scanner has the potential to reduce the in-vivo resolution limit of such measurements to scales that allow observing the very small-scale structures in bones. This could yield new insights on the cause, progression, or effect of bone diseases like osteoporosis. However, imaging of living mice aiming at resolutions of few micrometers is challenging because of the movement of the mouse throughout the scan which considerably degrades image quality. Therefore, motion compensation is crucial in this context. Here, one potential strategy for motion compensation in CT-like imaging – namely epipolar consistency - is presented and applied to simulated motion on X-ray microscopy projection data of ex-vivo mouse tibia bones.

References:
Epipolar Consistency in Transmission Imaging: https://ieeexplore.ieee.org/abstract/document/7094279
Next-generation imaging of the skeletal system and its blood supply: https://www.nature.com/articles/s41584-019-0274-y